Measure all ingredients using measuring spoons.
Add paprika, brown sugar, and garlic powder to a bowl.
Mix in onion powder, salt, black pepper, chili powder, cumin, and mustard powder.
Add cayenne pepper for extra heat, if desired.
Whisk all spices together until well combined.
Ensure the mixture is smooth and free of lumps.
Transfer the rub to an airtight container.
Close the container tightly to keep the rub fresh.
Rub the spice mixture generously onto the meat.
Press the rub into the meat using your hands.